Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods
ZEB represses transcription through interaction with the corepressor CtBP.
The interaction of the carboxyl terminus-binding protein with the Smad corepressor TGIF is disrupted by a holoprosencephaly mutation in TGIF.
Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C.
Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.
Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase.
Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP.
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.
The FoxP subclass in Xenopus laevis development.
Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP.
A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP.
ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.
TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints.
Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein.
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A.
Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.
C-terminal binding proteins (CtBPs) attenuate KLF4-mediated transcriptional activation.
A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity.
An atlas of combinatorial transcriptional regulation in mouse and man.
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.
Transcriptional regulation of BRCA1 expression by a metabolic switch.
A directed protein interaction network for investigating intracellular signal transduction.
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.
Toward an understanding of the protein interaction network of the human liver.
PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1.
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP.
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
EXD2 promotes homologous recombination by facilitating DNA end resection.
A High-Density Map for Navigating the Human Polycomb Complexome.
Architecture of the human interactome defines protein communities and disease networks.
ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin.
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
A pathogenic CtBP1 missense mutation causes altered cofactor binding and transcriptional activity.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Identification and functional characterization of transcriptional activators in human cells.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.
Multimodal cell maps as a foundation for structural and functional genomics.
Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.
A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis.
Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif.
PRC1 SUMOylates CTBP1 with SUMO2,3
PRC1 SUMOylates CTBP1 with SUMO1
beta-catenin is replaced by repression complexes at the promoter
APC promotes disassembly of beta-catenin transactivation complex
TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes
TFC7L2 mutants don't bind CTBP
CTBP1,CTBP2 binds CDH1 gene promoter