Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation.

Next-generation sequencing to generate interactome datasets.

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

Alternative translation initiation augments the human mitochondrial proteome.

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.

Ribosome. The structure of the human mitochondrial ribosome.

Structure and Function of the Mitochondrial Ribosome.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP

MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA

55S ribosome:MTRF1L hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed

Hydrolysis of GTP and dissociation of 28S and 39S subunits

GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA

MRRF binds 55S ribosome:mRNA:tRNA

55S ribosome:MTRF1 hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed

Stalled 55S mitochondrial ribosome is dissociated to yield 28S subunit and 39S subunit:mRNA:peptidyl-tRNA:tRNA

MTRF1 and GTP bind 55S ribosome:MT-CO1,MT-ND6 mRNA:peptidyl-tRNA at P-site:tRNA at E-site

ICT1 hydrolyzes the peptidyl-tRNA bond of the nascent polypeptide

55S mitochondrial ribosome:non-stop mRNA binds ICT1 (MRPL58)

Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome.

Structural basis of mitochondrial translation.

Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.