Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniPathway vocabulary mapping
Combined Automated Annotation using Multiple IEA Methods
YeastPathways to GO-CAM conversion
Preliminary characterization of Yor180Cp: identification of a novel peroxisomal protein of saccharomyces cerevisiae involved in fatty acid metabolism.
Alternatives to the isomerase-dependent pathway for the beta-oxidation of oleic acid are dispensable in Saccharomyces cerevisiae. Identification of YOR180c/DCI1 encoding peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase.
Evidence for a novel pathway for the targeting of a Saccharomyces cerevisiae peroxisomal protein belonging to the isomerase/hydratase family.
A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast.
UniProt entry Q08558 (DCI1)
SGD gene description for DCI1 (yeast)
Oleate beta-oxidation in yeast involves thioesterase but not Yor180c protein that is not a dienoyl-CoA isomerase.
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Purified MBP-Yor180c (Dci1) fusion protein has no dienoyl-CoA isomerase activity, and the yor180c deletion does not lower cellular dienoyl-CoA isomerase activity.
"Firstly, the deletion of the YOR180c gene did not eliminate the dienoyl-CoA isomerase activity and secondly, the purified fusion protein of Yor180c protein and maltose binding protein did not have any dienoyl-CoA isomerase activity."
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yor180c deletion cells grow like wild type on oleic or palmitic acid.
"Growth of wild-type cells was indistinguishable from that of YOR180c mutant cells on either palmitic acid or oleic acid"