Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Characterization of two alpha-galactosidase mutants (Q279E and R301Q) found in an atypical variant of Fabry disease.

Overexpression of human alpha-galactosidase A results in its intracellular aggregation, crystallization in lysosomes, and selective secretion.

Comparison of the effects of agalsidase alfa and agalsidase beta on cultured human Fabry fibroblasts and Fabry mice.

Alpha-galactosidase A gene rearrangements causing Fabry disease. Identification of short direct repeats at breakpoints in an Alu-rich gene.

Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

A novel mutation of α-galactosidase A gene causes Fabry disease mimicking primary erythromelalgia in a Chinese family.

Synthesis and processing of alpha-galactosidase A in human fibroblasts. Evidence for different mutations in Fabry disease.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Quantitative fragmentomics allow affinity mapping of interactomes.

Studies on human liver alpha-galactosidases. I. Purification of alpha-galactosidase A and its enzymatic properties with glycolipid and oligosaccharide substrates.

Multimodal cell maps as a foundation for structural and functional genomics.

Affinity purification of alpha-galactosidase A from human spleen, placenta, and plasma with elimination of pyrogen contamination. Properties of the purified splenic enzyme compared to other forms.

ConA-mediated binding and uptake of purified alpha-galactosidase A in Fabry fibroblasts.

Molecular basis of Fabry disease: mutations and polymorphisms in the human alpha-galactosidase A gene.

Only sphingolipid activator protein B (SAP-B or saposin B) stimulates the degradation of globotriaosylceramide by recombinant human lysosomal alpha-galactosidase in a detergent-free liposomal system.

GLA hydrolyzes PSAP(195-273):Gb3Cer:PE

Exocytosis of azurophil granule lumen proteins

GLA hydrolyzes PSAP(195-273):Gal2Cer:PE

The molecular defect leading to Fabry disease: structure of human alpha-galactosidase.

Curator notes on GLA GO annotation review

Falcon deep research on human GLA / alpha-galactosidase A

UniProtKB record for human GLA / alpha-galactosidase A