Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Electronic Gene Ontology annotations created by ARBA machine learning models
LvsA, a protein related to the mouse beige protein, is required for cytokinesis in Dictyostelium.
WD repeat domains target dictyostelium myosin heavy chain kinases by binding directly to myosin filaments.
Differential localization of the Dictyostelium kinase DPAKa during cytokinesis and cell migration.
Probing nucleotide dissociation from myosin in vitro using microgram quantities of myosin.
Keratocyte-like locomotion in amiB-null Dictyostelium cells.
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Myosin II is dispensable for unidirectional keratocyte-like movement but maintains cell shape.
"myosin II is dispensable for the unidirectional movement, though it likely"
Dictyostelium myosin bipolar thick filament formation: importance of charge and specific domains of the myosin rod.
Computer-assisted analysis of filopod formation and the role of myosin II heavy chain phosphorylation in Dictyostelium.
Subsecond reorganization of the actin network in cell motility and chemotaxis.
Evidence against essential roles for subdomain 1 of actin in actomyosin sliding movements.
Contractile ring-independent localization of DdINCENP, a protein important for spindle stability and cytokinesis.
Dictyostelium myosin II mechanochemistry promotes active behavior of the cortex on long time scales.
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Myosin II is highly enriched in the cell cortex and regulates cortical dynamics.
"Highly enriched in the cell cortex, actin, myosin II"
Blebbing of Dictyostelium cells in response to chemoattractant.
A point mutation in the SH1 helix alters elasticity and thermal stability of myosin II.
Dissection of amoeboid movement into two mechanically distinct modes.
Functional characterization of the N-terminal region of myosin-2.
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Truncations of Dictyostelium myosin-2 alter motile activity and actin/ADP affinity, and the SH3-like subdomain modulates motor activity.
"changes of similar extent in the affinity for ADP and"
Time-resolved responses to chemoattractant, characteristic of the front and tail of Dictyostelium cells.
Kinetic characterization of the function of myosin loop 4 in the actin-myosin interaction.
Actin-based propulsive forces and myosin-II-based contractile forces in migrating Dictyostelium cells.
Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions.
Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR.
An Elmo-like protein associated with myosin II restricts spurious F-actin events to coordinate phagocytosis and chemotaxis.
Visualizing myosin-actin interaction with a genetically-encoded fluorescent strain sensor.
Proteome analysis of Legionella vacuoles purified by magnetic immunoseparation reveals secretory and endosomal GTPases.
Cell adhesion molecules regulate contractile ring-independent cytokinesis in Dictyostelium discoideum.
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Double knockouts of mhcA (myosin II) with paxB or vinA have more severe cytokinesis defects, confirming myosin II's role in furrow-based division.
"Double knockout strains lacking mhcA, which codes for myosin II"
PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells.
Roles of an unconventional protein kinase and myosin II in amoeba osmotic shock responses.
Unique charge distribution in surface loops confers high velocity on the fast motor protein Chara myosin.
A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiency.
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Myosin II is present in the concentric protein rings of the phagocytic furrow.
"concentric overlapping rings of MyoK, Abp1, Arp3, coronin, and myosin II"
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke.
14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis.
Structural and functional impact of site-directed methionine oxidation in myosin.
Actin cross-linking proteins cortexillin I and II are required for cAMP signaling during Dictyostelium chemotaxis and development.
A mechanosensory system governs myosin II accumulation in dividing cells.
α-catenin and IQGAP regulate myosin localization to control epithelial tube morphogenesis in Dictyostelium.
Delineating the core regulatory elements crucial for directed cell migration by examining folic-acid-mediated responses.
Myosin-II-mediated directional migration of Dictyostelium cells in response to cyclic stretching of substratum.
Expression and characterization of a functional myosin head fragment in Dictyostelium discoideum.
Changes in the association of actin-binding proteins with the actin cytoskeleton during chemotactic stimulation of Dictyostelium discoideum.
The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes.
Quantitative immunochemical studies of myosin in Dictyostelium discoideum.
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Nearly half of cellular myosin partitions with the Triton-insoluble cytoskeleton and is released by ATP.
"If ATP is present, 98% of that myosin is released"
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum.
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mhcA is a cytoskeletal gene, differentially regulated during development and required for motility.
"the cytoskeletal genes abpA or mhcA, which are also required for motility"
Proteomic profiling of the extracellular matrix (slime sheath) of Dictyostelium discoideum.
Microtubule-Mediated Inositol Lipid Signaling Plays Critical Roles in Regulation of Blebbing.
Gene replacement in Dictyostelium: generation of myosin null mutants.
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Eliminating the conventional myosin gene abolishes normal cell division in suspension and impairs sporogenesis.
"the conventional myosin gene is required for growth in suspension, normal"
Intermolecular versus intramolecular interactions of Dictyostelium myosin: possible regulation by heavy chain phosphorylation.
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Myosin molecules self-associate into parallel dimers and tetramers via tail-tail interactions during filament assembly.
"Parallel dimers form tetramers by way of antiparallel interactions in their tail"
Contractility kits promote assembly of the mechanoresponsive cytoskeletal network.
Electron microscopic localization of myosin II and ABP-120 in the cortical actin matrix of Dictyostelium amoebae using IgG-gold conjugates.
Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination.
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Myosin heavy chain disruption produces multinucleate cells defective in cytokinesis; hmm cells aggregate but are blocked later in development.
"genetic proof that the intact myosin molecule is required for cytokinesis"
The lectin Discoidin I acts in the cytoplasm to help assemble the contractile machinery.
Adaptive pathfinding by nucleokinesis during amoeboid migration.
Inchworm migration facilitates amoeboid cell adaptation to high-adhesion environments.
The RNA-binding protein RNP1A is essential and interacts with contractility kit proteins to facilitate cell mechanics.
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Myosin II, cortexillin I and IQGAP1 assemble in the cytoplasm into mechanoresponsive contractility kits.
"myosin II, cortexillin I and IQGAP1 assemble in the cytoplasm into"
Talin force coupling underlies eukaryotic cell-substrate adhesion.
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. Isolation and characterization of myosin from amoebae of Dictyostelium discoideum.
Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development.
Myosin dynamics in live Dictyostelium cells.
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GFP-myosin concentrates in the cleavage furrow during cytokinesis and in the posterior cortex of migrating cells, and transiently in retracting pseudopod tips.
"GFP-myosin is concentrated in the cleavage furrow during cytokinesis and in the"
Dictyostelium cell shape generation requires myosin II.
A novel role for clathrin in cytokinesis.