Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Shy1p occurs in a high molecular weight complex and is required for efficient assembly of cytochrome c oxidase in yeast.
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Shy1 is required for efficient complex IV assembly but residual normal enzyme can still form.
"Steady-state levels of the enzyme were found to be strongly reduced, the total amount of assembled complex being approximately 30% of control."
Mss51p and Cox14p jointly regulate mitochondrial Cox1p expression in Saccharomyces cerevisiae.
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Shy1 likely acts downstream of the Cox14-Cox1-Mss51 regulatory complex.
"The release of Mss51p from the complex occurs at a downstream step in the assembly pathway, probably catalyzed by Shy1p."
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.
Shy1 couples Cox1 translational regulation to cytochrome c oxidase assembly.
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Shy1 is a complex IV assembly factor that interacts with Cox1 translational regulators and assembly intermediates.
"Shy1 interacts with Mss51 and Cox14, translational regulators of Cox1."
Coa1 links the Mss51 post-translational function to Cox1 cofactor insertion in cytochrome c oxidase assembly.
Quantitative variations of the mitochondrial proteome and phosphoproteome during fermentative and respiratory growth in Saccharomyces cerevisiae.
Pls1 Is a Peroxisomal Matrix Protein with a Role in Regulating Lysine Biosynthesis.
SHY1, the yeast homolog of the mammalian SURF-1 gene, encodes a mitochondrial protein required for respiration.
Falcon deep research report on SHY1