wdr-23: exact selected product and same-gene reference

Selected S6FN32 has 498 residues; reference P90794 has 571 residues.

Biopython PairwiseAligner global BLOSUM62, gap open -10, extension -0.5.

Reference interval Selected interval Identical residues
74–571 1–498 498

Reference feature mapping (sequence coverage does not establish retained function):

Reference feature Interval Mapped / length Identical
Repeat: WD 1 162–201 40 / 40 40
Repeat: WD 2 266–305 40 / 40 40
Repeat: WD 3 309–349 41 / 41 41
Repeat: WD 4 357–396 40 / 40 40
Repeat: WD 5 435–479 45 / 45 45
Repeat: WD 6 482–521 40 / 40 40

A shared segment does not establish that a truncated product folds, is expressed, localizes, or catalyzes the full-length reaction.

Inputs are the sibling frozen ProtNLM source and same-gene reference JSON files. Reproduce with UV_NO_SYNC=1 uv run python compare_sequences.py from this directory.