GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

PMID:22988102

Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates.

The E. coli study establishes ClsC as a PLD-family cardiolipin synthase with chemistry distinct from ClsA and ClsB.

"the combined YmdB-ClsC used PE as the phosphatidyl donor"

file:PSEPK/PP_5276/PP_5276-uniprot.txt

UniProtKB entry for PP_5276 (Q88CA5)

UniProt records the ClsC PANTHER subfamily assignment and two PLD domains.

"PTHR21248:SF12; CARDIOLIPIN SYNTHASE C; 1."

file:PSEPK/PP_5276/PP_5276-bioinformatics/RESULTS.md

PP_5276 HKD motif check

Both PLD HxK(x4)D motifs are intact.

"PP_5276 retains both PLD-superfamily HxK(x4)D catalytic motifs"