Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.

Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.

AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex

NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex

CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus

COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex

COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex

Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome.

Publisher Correction: Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice.

Disruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome.

Investigation of testis proteome alterations associated with male infertility in Dcaf17-deficient mice.

UniProt entry for DDB1- and CUL4-associated factor 17

DCAF17 source evidence and assay scope