Electronic Gene Ontology annotations created by ARBA machine learning models
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
Crystal structure of Escherichia coli MazG, the regulator of nutritional stress response.
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E. coli MazG is a tandem-domain enzyme whose active C-terminal domain hydrolyzes all eight canonical nucleoside triphosphates and affects survival under nutrient stress.
"The MazG-ATP complex structure and subsequent mutagenesis studies explain the peculiar active site environment accommodating all eight canonical NTPs as substrates."
QuickGO GOA annotations for mazG
OpenScientist pathway research for PSEPK pantothenate and CoA biosynthesis
PSEPK UniProt gene metadata table
OpenScientist gene research for mazG
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The report supports the tandem-domain NTP pyrophosphohydrolase assignment through close E. coli orthology and conserved catalytic motifs, while finding no direct KT2440 experiment and treating stringent-response coupling as an inference.
"No primary experimental study has been published on the *P. putida* KT2440 protein itself."