Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Combined Automated Annotation using Multiple IEA Methods

A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia.

Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase.

Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module.

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis.

A reference map of the human binary protein interactome.

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

Metallochaperone inserts 2Cu2+ into MT-CO2

COX18 inserts nascent MT-CO2 in COX20:TMEM77

UniProtKB Q5RI15 (COX20_HUMAN) curated entry