GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000041
Gene Ontology annotation based on UniPathway vocabulary mapping
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:12859189
Human arginase II: crystal structure and physiological role in male and female sexual arousal.
PMID:16128822
Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies. Alteration of substrate specificity by replacement of Asn149 with Asp.
PMID:22928666
Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging.
PMID:28614294
Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
PMID:34800366
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
PMID:8898077
Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line.
PMID:9144563
Chromosomal localization of the human arginase II gene and tissue distribution of its mRNA.
Reactome:R-HSA-452036
arginine + H2O => ornithine + urea [ARG2]
Reactome:R-HSA-9838035
CLPXP binds mitochondrial matrix proteins
Reactome:R-HSA-9838081
LONP1 degrades mitochondrial matrix proteins
Reactome:R-HSA-9838093
LONP1 binds mitochondrial matrix proteins
Reactome:R-HSA-9838289
CLPXP degrades mitochondrial matrix proteins
PMID:16545622
Spatial gene expression in the T-stage mouse metanephros.
PMID:25009204
Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation.
PMID:27074721
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.
PMID:27214549
Increased mitochondrial arginine metabolism supports bioenergetics in asthma.
PMID:27745970
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.
PMID:31751318
Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy.
PMID:23832324
Arginase-II induces vascular smooth muscle cell senescence and apoptosis through p66Shc and p53 independently of its l-arginine ureahydrolase activity: implications for atherosclerotic plaque vulnerability.
PMID:25484082
ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis.
file:human/ARG2/ARG2-uniprot.txt
UniProtKB P78540 (ARG2_HUMAN), normally fetched record
PMID:21820050
Angiotensin II stimulates in vitro branching morphogenesis of the isolated ureteric bud.