Gene Ontology annotation through association of InterPro records with GO terms

Combined Automated Annotation using Multiple IEA Methods

Convergent peripheral pathways catalyze initial glucose catabolism in Pseudomonas putida: genomic and flux analysis.

Three peripheral glucose pathways converge at 6-phosphogluconate in KT2440.

"glucose catabolism in Pseudomonas putida occurs through the simultaneous operation of three pathways that converge at the level of 6-phosphogluconate"

Regulation of Pyrroloquinoline Quinone-Dependent Glucose Dehydrogenase Activity in the Model Rhizosphere-Dwelling Bacterium Pseudomonas putida KT2440.

Periplasmic Gcd produces gluconic acid using PQQ as redox coenzyme.

"Soil-dwelling microbes solubilize mineral phosphates by secreting gluconic acid, which is produced from glucose by a periplasmic glucose dehydrogenase (GDH) that requires pyrroloquinoline quinone (PQQ) as a redox coenzyme."

PMID:20581202

Compartmentalized glucose metabolism in Pseudomonas putida is controlled by the PtxS repressor.

Approximately half of glucose uptake flows through the 2-ketogluconate peripheral pathway.

"about 50% of glucose taken up by the cells is channeled through the 2-ketogluconate peripheral pathway"

PMID:23392768

Influence of periplasmic oxidation of glucose on pyoverdine synthesis in Pseudomonas putida S11.

Gcd-dependent periplasmic glucose oxidation influences pyoverdine production through acid production.

"periplasmic oxidation of glucose to gluconic acid decreases the pH of MGM and thereby influences pyoverdine synthesis"

file:PSEPK/gcd/gcd-uniprot.txt

UniProt record for Pseudomonas putida KT2440 Gcd

file:PSEPK/gcd/gcd-notes.md

Curator notes for Pseudomonas putida KT2440 gcd

The notes record the five-helix membrane anchor used for the CC decision.

"Membrane-bound with 5 predicted transmembrane helices (aa 12-142)"

file:PSEPK/gcd/gcd-deep-research-falcon.md

Falcon deep-research report for Pseudomonas putida KT2440 gcd

The report places Gcd at the entry to the periplasmic oxidation cascade.

"This enzyme is a key entry point into the **periplasmic oxidation cascade (POC)**"