dpm-1: ProtNLM function review

Exact emitted record, retrieved 2026-09-10T14:34:37.287561+00:00.

Original prediction and assessment

Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins

NPI (CS 0). The full GDP-mannose-to-dolichol-phosphate transfer reaction requires a glycosyltransferase domain absent from the input. No full-length donor annotation can rescue that missing architecture. The glycosylation pathways listed are valid consequences of the full-length enzyme reaction, but not demonstrated functions of this peptide. Sequence and domain mapping; DPM complex study.

The assessment concerns the selected accession U4PF58. Other emitted outputs and evidence context.