COQ3 (human, Q9NZJ6) review notes
- Deep research: no provider deep-research file is available (no API keys in this session); the review
rests on UniProt Q9NZJ6, the cached literature and Reactome entries.
- Human COQ3 rescues yeast coq3 null and is active in vitro PMID:10777520.
- The 2024 in vitro reconstitution used ancestral proteins PMID:38425362,
PMID:38425362.
The IDA rows from this paper are accepted (the activity agrees with the human-enzyme data) but noted.
- Complex Q membership: PMID:27499296
(full text re-fetched; the earlier cache held only the introduction).
- Bare protein-binding rows (Floyd 2016 COQ partners; HuRI Y2H partners) removed per the protein-binding policy.
- glycerol metabolic process (IGI) removed: it reflects respiratory growth on glycerol, not glycerol metabolism.
- O-methyltransferase (IGI) modified to both specific activities (GO:0010420, GO:0061542), matching the module's two COQ3 annotons and yeast COQ3.