Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Fibrinogen interactions with ICAM-1 (CD54) regulate endothelial cell survival.
Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro).
The human plasma proteome: a nonredundant list developed by combination of four separate sources.
Fibrinogen and fragment D-induced vascular constriction.
Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance.
Congenital hypofibrinogenemia: characterization of two missense mutations affecting fibrinogen assembly and secretion.
Fibrinogen-induced endothelin-1 production from endothelial cells.
Crystal structure of human fibrinogen.
Identification of human plasma proteins as major clients for the extracellular chaperone clusterin.
Hepatitis C virus core protein interacts with fibrinogen-beta and attenuates cytokine stimulated acute-phase response.
Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
The role of fibrin matrices and tissue factor in early-term trophoblast proliferation and spreading.
The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis.
Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
MatrisomeDB 2.0: 2023 updates to the ECM-protein knowledge database.
gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors.
Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen.
Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets.
Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway.
The role of betagamma and alphagamma complexes in the assembly of human fibrinogen.
A mitogenic action for fibrinogen mediated through intercellular adhesion molecule-1.
Crystal structure of fragment double-D from human fibrin with two different bound ligands.
Adhesion of integrin αIIbβ3 to fibrin network
fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B
n fibrin monomers -> fibrin multimer
fibrin multimer -> fibrin multimer, crosslinked + NH4+
MyD88 forms a complex with TIRAP:activated TLR2/4
IRAK4 binds to the activated TLR receptor:TIRAP:MyD88 complex
IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP
Multiple IRAK1 autophosphorylation steps
Dissociation of hp-IRAK1:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex
Interaction of integrin alphaDbeta2 with fibrin
Interaction of integrin alphaXbeta2 with fibrin
Activated TLR2/4 interacts with MAL (TIRAP)
TIRAP is phosphorylated by BTK
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex
Activated TLR2/4:TIRAP interacts with BTK
Translocation of PTK2 to Focal complexes
Autophosphorylation of PTK2 at Y397
Recruitment of GRB2 to p-PTK2
Phosphorylation of pPTK2 by SRC
Interaction of integrin alphaIIb beta3 with Fibrinogen
Interaction of SOS with GRB2 bound to FADK1
Phosphorylation of BCAR1 by SRC-PTK2 complex
Recruitment of BCAR1 to PTK2 complex
Autophosphorylation of SRC
Clustering of Integrin alphaIIb beta3 complexes
Dephosphorylation of inactive SRC by PTPB1
SYK binds to integrin alphaIIb beta3
Exocytosis of platelet alpha granule contents
Defective IRAK4 does not bind MyD88:MAL:BTK:activated TLR2/4
Defective MyD88 does not oligomerize within the activated TLR2/4 complex
Defective MyD88 does not bind MAL(TIRAP):TLR2/4
Cleaved fibrinogen products bind TLR4:LY96
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex
MyD88 oligomerization within the complex of activated TLR:TIRAP:MyD88
αIIbβ3:fibrin multimer ->αIIbβ3:fibrin multimer, crosslinked + NH4+
fibrinogen + β-amyloid fibril:Zn2+ -> fibrinogen:β-amyloid fibril:Zn2+
Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling.
Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Leptin induces inflammation-related genes in RINm5F insulinoma cells.
Proteomics of microparticles after experimental pulmonary embolism.