GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
GO_REF:0000121
RGD ISO annotations to rat from other mammalian species
PMID:21051541
Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes.
PMID:19539030
TDP-43 localizes in mRNA transcription and processing sites in mammalian neurons.
PMID:21127054
Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.
PMID:21608013
Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: implications for protein misfolding and TDP-43 regulation.
PMID:21358640
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
PMID:21358643
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
PMID:26250685
TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.
PMID:11285240
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping.
PMID:21131904
TDP-43 regulates its mRNA levels through a negative feedback loop.
PMID:28335005
TDP-43 suppresses tau expression via promoting its mRNA instability.
PMID:17481916
TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein.
PMID:7745706
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.
PMID:26735904
ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.
PMID:27545621
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
PMID:29511089
TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.
PMID:30464263
TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle.
PMID:27123980
USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock.
PMID:18305152
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression.
PMID:27348499
The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.
PMID:28585542
Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity.
PMID:27378374
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses.
PMID:18836447
Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein.