GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

InterPro2GO transfers aminotransferase-family terms (transaminase activity, amino acid metabolism) and PLP binding; only PLP binding reflects SUR1's actual biochemistry.

GO_REF:0000033

Annotation inferences using phylogenetic trees

PAINT IBA from the tyrosine aminotransferase node transfers TAT activity and tyrosine catabolism to SUR1, a neofunctionalized C-S lyase subfamily member; cytosol IBA is appropriate.

GO_REF:0000122

AtSubP analysis

Predicts cytoplasmic localization.

PMID:14871316

Arabidopsis mutants in the C-S lyase of glucosinolate biosynthesis establish a critical role for indole-3-acetaldoxime in auxin homeostasis.

SUR1 is the glucosinolate C-S lyase; sur1 lacks aliphatic and indole glucosinolates, accumulates C-S lyase substrate, and its high-auxin phenotype arises from IAOx diversion into IAA.

"We report characterization of SUPERROOT1 (SUR1) as the C-S lyase in glucosinolate biosynthesis."

PMID:15851402

Auxin, ethylene and brassinosteroids: tripartite control of growth in the Arabidopsis hypocotyl.

Uses sur1/hls3 among hormone mutants to dissect hypocotyl growth; relevant only to the indirect auxin phenotype.

PMID:16377752

Proteomic analysis of different mutant genotypes of Arabidopsis led to the identification of 11 proteins correlating with adventitious root development.

sur1-3 is used as an auxin overproducer that spontaneously forms adventitious roots.

PMID:23073363

A novel C-S lyase from the latex-producing plant Taraxacum brevicorniculatum displays alanine aminotransferase and l-cystine lyase activity.

A SUR1-homologous PLP C-S lyase from Taraxacum is cytosolic, has L-cystine lyase and AlaAT but no TyrAT activity.

"However, we detected no in vitro tyrosine aminotransferase (TyrAT) activity"

PMID:25293756

A proteomic strategy for global analysis of plant protein complexes.

Detection in the crude leaf cytosolic fraction.

PMID:28887381

Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling.

High-throughput membrane fraction profiling; source of HDA mitochondrion.

PMID:32213638

REVERSAL OF RDO5 1, a Homolog of Rice Seed Dormancy4, Interacts with bHLH57 and Controls ABA Biosynthesis and Seed Dormancy in Arabidopsis.

Seed dormancy/ABA paper; neither the abstract nor the cached full text mentions SUR1 or fungal defense, and At2g20610 is absent from its accession list.

PMID:32612234

Extensive signal integration by the phytohormone protein network.

Large-scale Y2H phytohormone interactome; source of the protein binding IPI.

PMID:41819465

SUPERROOT1 is not the only C-S lyase capable to contribute to glucosinolate biosynthesis in Arabidopsis thaliana.

sur1 retains significant indolic glucosinolates, implying an additional C-S lyase; elevated auxin in sur1 depends on MYB34.

"we show that elevated auxin production in the sur1 plant depends on the MYB34 transcription factor"

PMID:8589625

Superroot, a recessive mutation in Arabidopsis, confers auxin overproduction.

Original superroot mutant description; sur1 has excess adventitious and lateral roots and elevated free and conjugated IAA.

PMID:21712415

Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis.