Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
The CD3 epsilon subunit of the TCR contains endocytosis signals.
Fourteen years' follow-up of an autoimmune patient lacking the CD3 gamma subunit of the T-lymphocyte receptor.
Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells.
The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.
Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells.
Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation.
[Overexpression of Bcl-2 inhibited T lymphocyte apoptosis mediated by CD3 epsilon molecule].
SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates.
Activation-induced ubiquitination of the T cell antigen receptor.
Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif.
Relevance of CD6-mediated interactions in T cell activation and proliferation.
Stoichiometry of the murine gammadelta T cell receptor.
FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection.
Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon.
Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70.
Structural basis of PxxDY motif recognition in SH3 binding.
Interaction between the N-terminal SH3 domain of Nck-alpha and CD3-epsilon-derived peptides: non-canonical and canonical recognition motifs.
Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.
Regulatory mechanisms in T cell receptor signalling.
T cell receptor signaling for γδT cell development.
Structural basis of assembly of the human T cell receptor-CD3 complex.
A reference map of the human binary protein interactome.
ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion.
Proximity between LAG-3 and the T cell receptor guides suppression of T cell activation and autoimmunity.
Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance.
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.
Independent mutations of the human CD3-epsilon gene resulting in a T cell receptor/CD3 complex immunodeficiency.
Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling.
Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model.
Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.
T lymphocyte development in the absence of CD3 epsilon or CD3 gamma delta epsilon zeta.
TCR complex interacts with peptide antigen-presenting MHC Class I
Phosphorylation of ITAM motifs in CD3 complexes
Phosphorylation of ZAP-70 by Lck
Dephosphorylation of Lck-pY505 by CD45
Phosphorylation of SLP-76
Inactivation of Lck by Csk
Phosphorylation of TBSMs in LAT
Phosphorylation of PLC-gamma1
Change of PKC theta conformation
Recruitment of ZAP-70 to phosphorylated ITAMs
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases
TCR binds self-lipid-based antigen via CD1
TCR binds microbial lipid-based antigen via CD1
Inactivation of LCK by PTPN22
PTPN22 dephosphorylates ZAP70
UniProtKB entry P07766 (CD3E_HUMAN)
Falcon deep research report for human CD3E
Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling.
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy.
Phospho-mimetic CD3ε variants prevent TCR and CAR signaling.
IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses.
CD3 and immunoglobulin G Fc receptor regulate cerebellar functions.