Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family.

IRAK-M is a negative regulator of Toll-like receptor signaling.

Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4.

Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling.

Early and preferential induction of IL-1 receptor-associated kinase-M in THP-1 cells by LPS derived from Porphyromonas gingivalis.

The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.

A reference map of the human binary protein interactome.

Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation.

IRAK-M mediates Toll-like receptor/IL-1R-induced NFκB activation and cytokine production.

The structure function of the death domain of human IRAK-M.

IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity.

The IRAK-M death domain: a tale of three surfaces.

UniProt entry Q9Y616 (IRAK3_HUMAN)