Annotation inferences using phylogenetic trees

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.

FCHo proteins are nucleators of clathrin-mediated endocytosis.

Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning.

A proteome-scale map of the human interactome network.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells.

Recruitment of AP-2 complex and clathrin

AAK1 phosphorylates AP-2 mu subunit at T156

FCHo proteins bind nascent clathrin-coated pit

ARBB recruits GPCRs into clathrin-coated pits

F- and N- BAR domain proteins bind the clathrin-coated pit

CLASP proteins and cargo are recruited to the nascent clathrin-coated pit

Clathrin recruits PIK3C2A

Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2

Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses.

FCHO1 fine-tunes synaptic vesicle endocytosis in an activity-dependent manner.

Editorial Expression of Concern.

Erratum for the Report "FCHo Proteins Are Nucleators of Clathrin-Mediated Endocytosis" by W. M. Henne et al.

Author Correction: Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells.

F-BAR domain only protein 1 (FCHO1) deficiency is a novel cause of combined immune deficiency in human subjects.