GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
PMID:15377783
Crystal structure of the clathrin adaptor protein 1 core.
PMID:16548883
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection.
PMID:19946888
Defining the membrane proteome of NK cells.
PMID:23247405
Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.
PMID:27057418
Role of the epithelial cell-specific clathrin adaptor complex AP-1B in cell polarity.
PMID:9733768
Identification and characterization of novel clathrin adaptor-related proteins.
Reactome:R-HSA-182263
Degradation of MHC I Complex
Reactome:R-HSA-182279
Formation of MHC I:Nef:AP-1:PACS-1 Complex
Reactome:R-HSA-182286
Transport of MHC I:Nef:AP-1:PACS-1 Complex
Reactome:R-HSA-2130619
TGN-lysosomal vesicle coat assembly
Reactome:R-HSA-2130641
Translocation of TGN-lysosome vesicle to lysosome
Reactome:R-HSA-2213236
TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
Reactome:R-HSA-421831
trans-Golgi Network Coat Assembly
Reactome:R-HSA-421833
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture
Reactome:R-HSA-421835
trans-Golgi Network Vesicle Scission
Reactome:R-HSA-421836
trans-Golgi Network Derived Vesicle Uncoating
Reactome:R-HSA-432688
trans-Golgi Network Derived Lysosomal Vesicle Uncoating
Reactome:R-HSA-432706
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly
Reactome:R-HSA-432707
trans-Golgi Network Lysosomal Vesicle Scission
Reactome:R-HSA-432712
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane
Reactome:R-HSA-5333658
CLAT:AP1:CLVS bind PI(3,5)P2
Reactome:R-HSA-8951498
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex
PMID:39269494
Revising pathogenesis of AP1S1-related MEDNIK syndrome: a missense variant in the AP1S1 gene as a causal genetic lesion.
PMID:17360967
The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.
PMID:14691137
Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes.
PMID:21097499
Conservation and diversification of dileucine signal recognition by adaptor protein (AP) complex variants.
PMID:24843023
Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.
PMID:23415225
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1.
PMID:19057675
Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord.
PMID:32306098
AP1S1 missense mutations cause a congenital enteropathy via an epithelial barrier defect.
PMID:27411398
AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway.
PMID:20203623
AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory.
PMID:24754424
AP1S1 defect causing MEDNIK syndrome: a new adaptinopathy associated with defective copper metabolism.
PMID:37659097
Downregulation of AP1S1 causes the lysosomal degradation of EGFR in non-small cell lung cancer.
PMID:2040623
AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast.
PMID:41032520
Uncovering cargo clients and accessory factors of AP-1 and AP-4 through vesicle proteomics.
PMID:9714600
The AP-3 complex: a coat of many colours.
PMID:24928897
σ1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.
PMID:17003107
Fab1p and AP-1 are required for trafficking of endogenously ubiquitylated cargoes to the vacuole lumen in S. cerevisiae.
PMID:9335339
The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.
PMID:20870878
Endosomal and AP-3-dependent vacuolar trafficking routes make additive contributions to Candida albicans hyphal growth and pathogenesis.
PMID:19624755
Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast.
PMID:17289840
Molecular determinants for the interaction between AMPA receptors and the clathrin adaptor complex AP-2.
PMID:11102472
A conserved clathrin assembly motif essential for synaptic vesicle endocytosis.
file:human/AP1S1/AP1S1-uniprot.txt
UniProtKB entry P61966 (AP1S1_HUMAN), AP-1 complex subunit sigma-1A
file:human/AP1S1/AP1S1-bioinformatics/RESULTS.md
AP1S1 dileucine-site residue conservation analysis (this review)
file:human/AP1S1/AP1S1-deep-research-affinage.md
Affinage mechanistic annotation for AP1S1 (human)