Gene Ontology annotation through association of InterPro records with GO terms

Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects.

The study distinguishes serine proteases from their noncatalytic homologs by catalytic-triad conservation; the exact supplementary sequence for SPH244 was not retrieved.

"based on the presence or absence of the His-Asp-Ser catalytic triad"

file:DROME/CG34171/CG34171-bioinformatics/RESULTS.md

CG34171 isoform and catalytic-site analysis

file:DROME/CG34171/CG34171-flybase.txt

FlyBase FBgn0085200: CG34171 polypeptide identities

FlyBase records two unique polypeptides that arise from an alternative translation stop.

"Alternative translation stop created by use of multiphasic reading frames within coding region."
The gene's only phylogenetic (IBA) annotation is innate immune response, inherited from PANTHER node PTN000667087. FlyBase lists no IBA proteolysis row.

"PANTHER:PTN000667087"

file:DROME/CG34171/CG34171-uniprot.txt

UniProtKB X2JEK1: selected CG34171-PC record

The S1 domain call of X2JEK1 covers residues 38-161 of a 176-residue product.

"DOMAIN 38..161"

file:DROME/CG34171/CG34171-reference-A8DZ15-uniprot.txt

UniProtKB A8DZ15: CG34171-PB record