Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa.
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The PAO1 rpoS mutant is hypersensitive to heat, osmolarity and H2O2.
"In addition, the PAO1 rpoS mutant was hypersensitive to heat shock at 50°C, increased osmolarity, and prolonged exposure to high concentrations of H 2 O 2 ."
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The rpoS mutant overproduces pyocyanin and pyoverdine.
"The rpoS mutation resulted in the increased production of the phenazine antibiotic pyocyanin and the siderophore pyoverdine."
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The rpoS mutant has altered twitching motility.
"In addition, the rpoS mutant displayed an altered twitching-motility phenotype, suggesting that the colonization factors, type IV fimbriae, were affected."
Expression of Pseudomonas aeruginosa aer-2, one of two aerotaxis transducer genes, is controlled by RpoS.
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RpoS is required for Aer-2-mediated aerotaxis and transcription of the aer-2 operon.
"A deletion-insertion mutation of alternative sigma factor RpoS eliminated Aer-2-mediated aerotaxis but not Aer-mediated aerotaxis."
Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA.
Connected partner-switches control the life style of Pseudomonas aeruginosa through RpoS regulation.
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The anti-sigma domain of HsbR binds RpoS.
"Clearly, HsbRD3 interacted with RpoS from P. aeruginosa as well as with CrsR."
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HsbR is an anti-sigma factor controlling RpoS.
"We established that HsbR is an anti-sigma factor controlling RpoS and unveiled a connection between the HptB-HsbR-HsbA signal transduction cascade and the RpoS pathway during biofilm biogenesis."
Defining the regulatory mechanisms of sigma factor RpoS degradation in Azotobacter vinelandii and Pseudomonas aeruginosa.
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RssB and RssC are needed for ClpXP-dependent RpoS degradation.
"We propose that both RssB and RssC are necessary for the ClpXP-dependent RpoS degradation during exponential growth in two species of the Pseudomonadaceae family."
Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods