Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity.
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Colorectal cancer in mice genetically deficient in the mucin Muc2.
c-Myc represses the murine Nramp1 promoter.
Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor.
Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis.
c-Myc-deficient B lymphocytes are resistant to spontaneous and induced cell death.
c-Myc augments gamma irradiation-induced apoptosis by suppressing Bcl-XL.
Miz1 is required for early embryonic development during gastrulation.
Serine-threonine kinases and transcription factors active in signal transduction are detected at high levels of phosphorylation during mitosis in preimplantation embryos and trophoblast stem cells.
A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation.
PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.
Identification of a novel c-Myc protein interactor, JPO2, with transforming activity in medulloblastoma cells.
c-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells.
Neural crest cell deficiency of c-myc causes skull and hearing defects.
Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.
Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1.
Pim kinase-dependent inhibition of c-Myc degradation.
Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma.
A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.
C-myc as a modulator of renal stem/progenitor cell population.
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.
Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc.
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.
An atlas of combinatorial transcriptional regulation in mouse and man.
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication.
c-Myc regulates transcriptional pause release.
A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.
TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC.
Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation.
TRIM6 interacts with Myc and maintains the pluripotency of mouse embryonic stem cells.
Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.
Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.
Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis.
Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response.
Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.
Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.
TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network.
Integrative analysis reveals histone demethylase LSD1 promotes RNA polymerase II pausing.
Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.
Myc activates telomerase.
The C. elegans MDL-1 and MXL-1 proteins can functionally substitute for vertebrate MAD and MAX.
Myc gene expression is enhanced by E2f1, phospho-Stat3, and Cebpb and repressed by Cebpa
UniProt record for mouse Myc
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Myc is a transcription factor that recognizes E-box-like core sequences and requires Max dimerization for efficient DNA binding.
"Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX."
Bioreason deep research report on mouse Myc
Falcon deep research report on mouse Myc
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Myc is a nuclear bHLH-LZ transcription factor whose core activity is Myc-Max DNA binding and transcriptional regulation.
"c-Myc is best annotated as a sequence-specific nuclear transcription regulator / transcriptional amplifier that controls genes involved in cell cycle entry, proliferation, metabolism, ribosome biogenesis, differentiation, apoptosis, development, tissue homeostasis, and regeneration."