Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells.

A transmembrane intracellular estrogen receptor mediates rapid cell signaling.

G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol.

Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish.

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts.

G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments.

G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium.

Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway.

G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation.

G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection.

Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation.

NHERF1, a novel GPER associated protein, increases stability and activation of GPER in ER-positive breast cancer.

G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β(1)-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells.

Multiplexed mapping of the interactome of GPCRs with receptor activity-modifying proteins.

Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues.

G protein-coupled estrogen receptor 1 binds estrogen non-classically

Liganded Gi-activating GPCR acts as a GEF for Gi

The Ligand:GPCR:Gi complex dissociates

Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein

ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s

GPER:Heterotrimeric G-protein Gs binds ESTG

ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex

UniProt entry Q99527 (GPER1_HUMAN)