Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on absence of key sequence residues
Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships.
Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation.
Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects.
CG4793 catalytic-site and exact-sequence analysis
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The exact selected sequence has glycine replacing the catalytic serine of the S1 protease fold.
"In particular, the catalytic serine is replaced by glycine in the conserved local segment TCKGDGGAPLA."
UniProt Q8IP30 sequence and feature record
Bina et al. 2010 full article: verbatim PDF text extraction
The S1A protease family members CG10764 and CG4793 regulate cellular immunity in Drosophila.
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CG4793 depletion in lamellocytes increases parasitoid-egg encapsulation, supporting negative regulation of this immune response.
"Conversely, knockdown of CG4793 in lamellocytes resulted in a significant increase in the encapsulation rate."