Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Combined Automated Annotation using Multiple IEA Methods

Human phosphoribosylformylglycineamide amidotransferase (FGARAT): regional mapping, complete coding sequence, isolation of a functional genomic clone, and DNA sequence analysis.

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

CRISPR-Cas9 induced mutations along de novo purine synthesis in HeLa cells result in accumulation of individual enzyme substrates and affect purinosome formation.

FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi

Purine ribonucleoside monophosphate biosynthesis

UniProtKB entry O15067 (PUR4_HUMAN), phosphoribosylformylglycinamidine synthase