Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.
SWI/SNF chromatin remodeling and cancer.
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.
REST repression of neuronal genes requires components of the hSWI.SNF complex.
The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.
DNA-binding properties of ARID family proteins.
PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.
-
ARID2 contributes to PBAF target selectivity.
"The selectivity by PBAF requires a novel subunit, BAF200, but not the previously
described PBAF-specificity subunit, BAF180 (Polybromo)."
BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.
-
BRG1 immunoprecipitation from human J-Lat A2 cells recovers BAF200 within the associated remodeling complex.
"BRG-1 was immunoprecipitated from J-Lat A2 cells transfected with control siRNA or siRNA targeting BAF250 or BAF180, and its associated proteins were examined by SDS-PAGE and Western blotting with antibodies against BRG-1 itself, the BAF or PBAF-specific subunits BAF250a, BAF180 and BAF200, the core subunit INI-1 and GAPDH as control."
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin.
miR-208-3p promotes hepatocellular carcinoma cell proliferation and invasion through regulating ARID2 expression.
-
ARID2 overexpression inhibits proliferation and invasion in the tested HCC cells.
"miR-208-3p
down-regulation and ARID2 over-expression elicited similar inhibitory effects on
HCC cell proliferation and invasion."
The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.
-
ARID2 promotes RAD51 recruitment and homologous-recombination repair.
"Baf200 plays an important function by facilitating homologous
recombination-dependent processes, such as recruitment of Rad51 (a key component
of homologous recombination) to DSBs, homology-directed repair, and cell
survival after DNA damage."
Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
A protein interaction landscape of breast cancer.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
Diversity and specialization of mammalian SWI/SNF complexes.
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.
Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.
ARID2 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1
BRD7 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2
PHF10 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD7
PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10
Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression.
ARID2 literature and curation notes