PMID:16477007

Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence.

Extracts of a PA14 strain overexpressing PA2870 contained 96 pmol c-di-GMP per mg wet cell weight (Table 1, read in PMC full text; detection limit 12).

"Analysis of the phenotypes of DGC and PDE mutants and overexpressing clones revealed that certain virulence-associated traits are controlled by multiple DGCs and PDEs through alterations in c-di-GMP levels."

PMID:20978535

Specific control of Pseudomonas aeruginosa surface-associated behaviors by two c-di-GMP diguanylate cyclases.

A single-crossover PA2870 mutant in PA14 had no consistent biofilm defect.

"Only the single-crossover mutation in PA1107 resulted in a consistent observable biofilm defect (not shown)."

PMID:35935233

Phenotypic and integrated analysis of a comprehensive Pseudomonas aeruginosa PAO1 library of mutants lacking cyclic-di-GMP-related genes.

A PAO1 PA2870 deletion reduces early attachment.

"This was clearly observed for 7 mutations, PA0169, PA1120 (yfiN; Malone et al., 2010), PA2870, PA3702"

file:PSEAE/PA2870/PA2870-notes.md

PA2870 review notes

file:PSEAE/PA2870/PA2870-uniprot.txt

UniProt entry Q9HZX6

GO_REF:0000003

Gene Ontology annotation based on Enzyme Commission mapping

GO_REF:0000033

Annotation inferences using phylogenetic trees

GO_REF:0000044

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt