DCI1 (YOR180C; ECI2/EHD2; UniProt Q08558) notes

• Peroxisomal Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, EC 5.3.3.21 PMID:10455114.
• Weak intrinsic 3,2-isomerase activity in vitro, but not physiological PMID:10455114; dci1 grows like wild type on oleate PMID:10455114.
• Earlier study saw a mild oleate growth defect PMID:10381339.
• Peroxisomal matrix: GFP and matrix proteomics PMID:10381339; PTS-receptor-independent targeting PMID:10639339.
• Needed for efficient Eci1p import; two-hybrid interaction PMID:10381339.
• Oleate-induced via Oaf1/Pip2 ORE [UniProt:Q08558].

Pathway-context observations

• YeastPathways attaches DCI1 to the EC 5.3.3.8 (Delta3-Delta2-enoyl-CoA isomerase) step, which is ECI1's step. DCI1's real step is EC 5.3.3.21 (di-isomerase, auxiliary route via Sps19p 2,4-dienoyl-CoA reductase). RCA GO:0004165 reviewed as MODIFY -> GO:0051750.
• YEAST-FAO-PWY RCA "cytosol" is a conversion artefact (REMOVE).