PA14 to PAO1 mapping of the P. aeruginosa BCCT transporters BetT1, BetT2, BetT3

Question: Malek et al. 2011 (PMID:21478341) name the three BCCT transporters by PA14
locus tag (BetT1 PA14_70980, BetT2 PA14_12990, BetT3 PA14_69850). Which PAO1 loci are
they?

Method: map_pa14_betT.py fetches the PA14 and PAO1 protein sequences from UniProt and
computes global (Needleman-Wunsch, BLOSUM62) percent identity over aligned columns.
Run: uv run --no-project --with biopython python map_pa14_betT.py. Raw output: output.tsv.

Results

PA14 protein	PAO1 PA5375 (Q9HTI9)	PAO1 PA3933 (Q9HX83)	PAO1 PA5291 (Q9HTR3)
PA14_70980 BetT1 (A0A0H2ZIB8, 516 aa)	99.2%	54.8%	46.8%
PA14_12990 BetT2 (A0A0H2ZFQ2, 653 aa)	54.6%	100.0% (identical)	49.3%
PA14_69850 BetT3 (A0A0H2ZJC5, 661 aa)	47.2%	49.3%	100.0% (identical)

Conclusion

PA14_12990 BetT2 is identical to PAO1 PA3933, and PA14_69850 BetT3 is identical to PAO1
PA5291. BetT1 is PA5375. So in PAO1, BetT2 = PA3933 and BetT3 = PA5291.