Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Combined Automated Annotation using Multiple IEA Methods
Deep research summary for ARF19
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ARF19 is a nuclear A-class ARF transcription factor that binds AuxRE-containing promoters and functions redundantly with ARF7 in auxin-responsive lateral root development.
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Recent ARF literature refines TGTCNN AuxRE preferences, composite AuxRE grammar, and PB1-mediated ARF/AUX-IAA interaction logic relevant to ARF19 annotation.
GOA annotations for ARF19
Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
Functional genomic analysis of the AUXIN RESPONSE FACTOR gene family members in Arabidopsis thaliana: unique and overlapping functions of ARF7 and ARF19.
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arf7 arf19 double mutant has severely impaired lateral root formation
"arf7 arf19 has a strong auxin-related phenotype not observed in the arf7 and arf19 single mutants, including severely impaired lateral root formation"
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Auxin-induced gene expression is severely impaired in arf7 arf19
"Global gene expression analysis revealed that auxin-induced gene expression is severely impaired in the arf7 single and arf7 arf19 double mutants"
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ARF7 and ARF19 regulate overlapping sets of target genes
"The data suggest that the ARF7 and ARF19 proteins play essential roles in auxin-mediated plant development by regulating both unique and partially overlapping sets of target genes"
Developmental specificity of auxin response by pairs of ARF and Aux/IAA transcriptional regulators.
NPH4/ARF7 and ARF19 promote leaf expansion and auxin-induced lateral root formation.
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ARF19 activates transcription
"We show that ARF19, the fifth Q-rich ARF, also activates transcription"
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arf7 arf19 double mutant has decreased lateral root formation and leaf cell expansion
"in combination with mutations in NPH4/ARF7, encoding the most closely related ARF, they cause several phenotypes including a drastic decrease in lateral and adventitious root formation and a decrease in leaf cell expansion"
Tissue-specific expression of stabilized SOLITARY-ROOT/IAA14 alters lateral root development in Arabidopsis.
A role for auxin response factor 19 in auxin and ethylene signaling in Arabidopsis.
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arf19 mutant is auxin resistant
"Both arf19 and arf7 mutants isolated from our forward genetic screens are auxin resistant"
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arf19 has ethylene-insensitive roots
"In addition to being auxin resistant, arf19 has also ethylene-insensitive roots"
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ARF19 expression is induced by ethylene
"ARF19 expression is induced by ethylene treatment"
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ARF19 can complement arf7 at the protein level
"we show that a genomic fragment of ARF19 not only complements arf19, but also rescues arf7"
ARF7 and ARF19 regulate lateral root formation via direct activation of LBD/ASL genes in Arabidopsis.
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ARF7 and ARF19 directly regulate LBD16/ASL18 and LBD29/ASL16 transcription
"ARF7 and ARF19 directly regulate the auxin-mediated transcription of LATERAL ORGAN BOUNDARIES-DOMAIN16/ASYMMETRIC LEAVES2-LIKE18 (LBD16/ASL18) and/or LBD29/ASL16 in roots"
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arf7 arf19 double mutant is severely impaired in lateral root formation
"The arf7 arf19 double knockout mutant is severely impaired in lateral root formation"
Domain II mutations in CRANE/IAA18 suppress lateral root formation and affect shoot development in Arabidopsis thaliana.
The auxin signalling network translates dynamic input into robust patterning at the shoot apex.
BAT1, a putative acyltransferase, modulates brassinosteroid levels in Arabidopsis.
An Arabidopsis gene regulatory network for secondary cell wall synthesis.
Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.
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ARF19 binds PRC2 gene promoters
"Using enhanced yeast one-hybrid analysis, upstream regulators of the PRC2 member genes are identified"
CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping.
Arabidopsis ATXR2 deposits H3K36me3 at the promoters of LBD genes to facilitate cellular dedifferentiation.
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ARF7/ARF19 recruit ATXR2 to LBD promoters
"ATXR2 was recruited to LBD promoters by the transcription factors AUXIN RESPONSE FACTOR 7 (ARF7) and ARF19"
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arf7-1 arf19-2 double mutant is defective in callus formation
"Leaf explants from arf7-1arf19-2 double mutants were defective in callus formation and showed reduced H3K36me3 accumulation at LBD promoters"
LBD18 uses a dual mode of a positive feedback loop to regulate ARF expression and transcriptional activity in Arabidopsis.
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ARF7 and ARF19 directly bind AuxRE in LBD18 promoter
"We showed that ARF7 and ARF19 directly bind AuxRE in the LBD18 promoter"
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LBD18 interacts with ARF7 and ARF19 via PB1 domain
"LBD18 interacts with ARFs including ARF7 and ARF19 via the Phox and Bem1 domain of ARF"
JMJ30-mediated demethylation of H3K9me3 drives tissue identity changes to promote callus formation in Arabidopsis.
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JMJ30 binds to LBD promoters along with ARF7 and ARF19
"The JMJ30 protein binds to promoters of the LBD16 and LBD29 genes along with AUXIN RESPONSE FACTOR 7 (ARF7) and ARF19"
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ARF-JMJ30 complex catalyzes H3K9me3 removal at LBD loci
"The ARF-JMJ30 complex catalyzes the removal of methyl groups from H3K9me3, especially at the LBD16 and LBD29 loci"
Transcriptional regulation of nitrogen-associated metabolism and growth.
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ARF19 identified as regulator of nitrogen metabolism genes
"Here we present a transcriptional regulatory network and twenty-one transcription factors that regulate the architecture of root and shoot systems in response to changes in nitrogen availability"
Extensive signal integration by the phytohormone protein network.
The protein-protein interaction landscape of transcription factors during gynoecium development in Arabidopsis.
Protein-protein interactions among the Aux/IAA proteins.
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ARF19 (IAA24) discovered as interacting with IAA1
"Screening an Arabidopsis lambda-ACT cDNA library using IAA1 as a bait reveals heterotypic interactions of IAA1 with known and newly discovered members of the Arabidopsis Aux/IAA gene family"
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Dimerization occurs via C-terminal domains
"Deletion analysis of PS-IAA4 indicates that the betaalphaalpha containing acidic C terminus of the protein is necessary for homotypic interactions"
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Aux/IAA proteins are nuclear-localized
"The Aux/IAA family of early genes encodes proteins that are short-lived and nuclear-localized"