DELE1 notes

Deep research: not run (falcon/perplexity-lite unavailable). Review based on cached publications and UniProt.

• OMA1 cleaves DELE1; short form activates HRI in cytosol PMID:32132706
• Associated with inner membrane before cleavage PMID:32132707
• Iron deficiency: import arrest, full-length DELE1 on mitochondrial surface activates HRI; degraded by LONP1 at steady state PMID:37327776.
• DELE1-CTD oligomerizes PMID:37550454; HRI branch drives mitophagy PMID:38340717.
• No GO:0034514 on DELE1 in GOA; not added — the established triggers are depolarization/import failure and iron deficiency, not shown to be matrix protein misfolding specifically.