Gene Ontology annotation reference GO_REF:0000015
Gene Ontology annotation reference GO_REF:0000024
Gene Ontology annotation reference GO_REF:0000033
Identification of a nuclear gene (FMC1) required for the assembly/stability of yeast mitochondrial F(1)-ATPase in heat stress conditions.
CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets.
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Human FMC1 (C7orf55), the in-subfamily ortholog of CG34117, is mitochondrial. Its knockout destabilizes complex V, which re-expression rescues, and it binds the F1 assembly factor ATPAF2.
"C7orf55 is required for mitochondrial ATP synthase function and specifically that C7orf55 binds a known assembly factor of this complex"
CG34117 falcon deep research
CG34117 re-review sequence comparison with human FMC1 and yeast Fmc1