Gene Ontology annotation reference GO_REF:0000002
Gene Ontology annotation reference GO_REF:0000041
Gene Ontology annotation reference GO_REF:0000120
Gpdh3 re-review bioinformatics (isoform comparison, active-site and ortholog motif survey)
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D. melanogaster Gpdh3 has threonine at the position of the human GPD1 proton-acceptor lysine (K204) and glutamate at the middle glycine of the NAD-binding GxGxxG loop.
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The catalytic lysine is retained in obscura-group and willistoni Gpdh3 orthologs but replaced in the melanogaster group; the NAD-loop glutamate is conserved across the lineage.
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E1JIT1 (Gpdh3-PB) differs from Gpdh3-PA (Q8IN06) only by lacking a 14-residue segment after the C-terminal GPDH domain.
Genomic signatures of globally enhanced gene duplicate accumulation in the megadiverse higher Diptera fueling intralocus sexual conflict resolution.
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Gpdh2 and Gpdh3 are testis-biased, long-branch paralogs of the muscle-specific cytosolic Gpdh1.
"Glycerol 3 phosphate dehydrogenaseGpdh1cytosolicmuscle specific0Gpdh211Gpdh311"
Gpdh3 falcon deep research
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No primary literature characterizes Gpdh3/CG43343; historical "GPDH-3" refers to an alternatively processed isozyme of the classical Gpdh (Gpdh1) locus and must not be attributed to Gpdh3.
"No primary publication directly characterizing CG43343/E1JIT1 was identified"