oprD (OccD1, P32722) review notes

No deep-research provider was available. Sources: UniProt P32722 (Swiss-Prot), cached abstracts of
PMID:2118530, 2109575, 8843159, 8012497, 2120174; full text of PMID:22272184 (Eren et al. 2012).

Function

Basic amino acid/peptide channel [file:PSEAE/oprD/oprD-uniprot.txt "Porin with a specificity for basic amino acids"];
PMID:2118530.
Carbapenem entry PMID:22272184.
Reported serine protease activity PMID:8843159.

PseudoCAP IBA-seed assessment

PTN002160747 (porin activity) is shared by oprD, oprE and opdP, all reviewed in this batch with consistent verdicts.

PTN node	node term	n_seeds	leaf IBAs	seed annotation (term, evidence, PMID)	verdict	rationale	other seeds	IBD stands without this seed?
PTN002160747	GO:0015288 porin activity	3	24 (6 taxa)	GO:0015288, IMP, PMID:2120174 (PseudoCAP); also UniProt IDA PMID:2118530	INDIRECT-PHENOTYPE (PseudoCAP row)	Abstract: transductants lost four OM proteins (C, D2, E1, E2) at once, and the authors conclude only that at least one is a porin; the IMP cannot be attributed to OprD alone. The term is correct (UniProt IDA, structures, electrophysiology). PSEUDOCAP WRONG_EVIDENCE_CODE/CHECK, PROBABLE (same defect on oprE).	OpdP (Q9HVS0), OprE (G3XDA5)	Yes; OprD's own UniProt IDA (PMID:2118530) is the strongest seed. Node term suits the Occ channel clade. No GO_CENTRAL defect.

This gene carries the most direct evidence for the shared node; no node-level GO_CENTRAL defect is
needed, so none is recorded on any of the three porins.