Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

RGD ISO annotations to rat from other mammalian species

Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling.

The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4.

Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.

Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.

Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC).

UniProtKB entry Q62940 (NEDD4_RAT)

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Solution structure of a Nedd4 WW domain-ENaC peptide complex.

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.

Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking.

The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.

Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells.

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.

Abnormal development of the neuromuscular junction in Nedd4-deficient mice.

Manual literature synthesis for rat Nedd4