GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000117
Electronic Gene Ontology annotations created by ARBA machine learning models
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
GO_REF:0000121
RGD ISO annotations to rat from other mammalian species
PMID:10217258
Synthesis degradation, and subcellular localization of synaptotagmin IV, a neuronal immediate early gene product.
PMID:10397765
Functional and biochemical analysis of the C2 domains of synaptotagmin IV.
PMID:10646502
Synaptotagmin IV is present at the Golgi and distal parts of neurites.
PMID:15197251
Synaptotagmin IV regulates glial glutamate release.
PMID:15311271
Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4.
PMID:16618809
Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells.
PMID:18046461
JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release.
PMID:18508778
Analysis of the synaptotagmin family during reconstituted membrane fusion. Uncovering a class of inhibitory isoforms.
PMID:20303854
Synaptotagmin IV modulation of vesicle size and fusion pores in PC12 cells.
PMID:20688915
Rat and Drosophila synaptotagmin 4 have opposite effects during SNARE-catalyzed membrane fusion.
PMID:20735850
Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown.
PMID:21551071
Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells.
PMID:22939844
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
PMID:26750488
Upregulation and axonal transport of synaptotagmin-IV in the direct-pathway medium spiny neurons in hemi-parkinsonian rats induced by dopamine D1 receptor stimulation.
PMID:29166604
Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4.
PMID:30021165
Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca(2+)/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites.
PMID:7791877
Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins.
PMID:7892240
Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain.
PMID:9830048
Delineation of the oligomerization, AP-2 binding, and synprint binding region of the C2B domain of synaptotagmin.
PMID:7993622
Functional properties of multiple synaptotagmins in brain.
PMID:9162066
The evolutionary pressure to inactivate. A subclass of synaptotagmins with an amino acid substitution that abolishes Ca2+ binding.
PMID:19448629
Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release.
PMID:19136969
Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals.
PMID:18468511
Synaptotagmin IV regulates dense core vesicle (DCV) release in LbetaT2 cells.
PMID:15390175
Altered hippocampal short-term plasticity and associative memory in synaptotagmin IV (-/-) mice.
PMID:21576241
Somatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channels.
PMID:12135783
Non-polarized distribution of synaptotagmin IV in neurons: evidence that synaptotagmin IV is not a synaptic vesicle protein.
PMID:23999003
SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation.
file:rat/Syt4/Syt4-uniprot.txt
UniProt record P50232 (SYT4_RAT)
file:rat/Syt4/Syt4-deep-research-manual.md
Manual literature synthesis for rat Syt4