Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

Combined Automated Annotation using Multiple IEA Methods

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins.

X-Linked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration.

Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis.

The Sept4 septin locus is required for sperm terminal differentiation in mice.

Unique anti-apoptotic activity of EAAC1 in injured motor neurons.

NRAGE: a potential rheostat during branching morphogenesis.

ARTS mediates apoptosis and regeneration of the intestinal stem cell niche.

Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia.

Structural basis of caspase-7 inhibition by XIAP.

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.

Mechanism of XIAP-mediated inhibition of caspase-9.

Towards a proteome-scale map of the human protein-protein interaction network.

Che-1 activates XIAP expression in response to DNA damage.

S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.

XIAP discriminates between type I and type II FAS-induced apoptosis.

XIAP mediates NOD signaling via interaction with RIP2.

Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4).

XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling.

The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.

X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis.

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.

Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7.