GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/moaE/moaE-uniprot.txt

UniProtKB entry for moaE

file:ECOLI/moaE/moaE-uniprot.txt

UniProtKB entry P30749 (MOAE_ECOLI)

E. coli MoaE, the characterised ortholog, converts precursor Z to molybdopterin within a 2:2 MoaD-MoaE heterotetramer (PubMed-tied evidence).

"SUBUNIT: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits."

file:PSEPK/moaE/moaE-deep-research-openscientist.md

OpenScientist gene research for moaE

The report reviews the MoaD-MoaE molybdopterin synthase reaction and complex.

"The requirement for the thiocarboxylate form is strict: **only the thiocarboxylated MPT synthase complex is able to convert precursor Z to MPT in vitro** [PMID: 11459846](https://pubmed.ncbi.nlm.nih.gov/11459846/)."

file:interpro/panther/PTHR23404/PTHR23404-entries.csv

PANTHER representative entries for the molybdopterin synthase family

PTHR23404 contains MoaE catalytic subunits, including the E. coli exemplar P30749.

"P30749,Molybdopterin synthase catalytic subunit,protein,83333,Escherichia coli (strain K12),Escherichia coli (strain K12),moaE,150,,,True"