Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells.
SP3 acts as a positive regulator on the core promoter of human ZPK gene.
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades.
Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling.
An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.
Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1.
Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein.
MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2.
High-throughput RNAi screening reveals novel regulators of telomerase.
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors.
Structure and dynamics of the MKK7-JNK signaling complex.
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases.
A central chaperone-like role for 14-3-3 proteins in human cells.
Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli.
Phosphorylation of human JNKs by activated MKK4/MKK7
Fc epsilon receptor (FCERI) signaling
Phosphorylation of MEK7 by MEKK1
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
Activated TAK1 phosphorylates MKK4/MKK7
Anthrax lef cleaves target cell MAP2K7 (MEK7)
Deep research report on MAP2K7 (Falcon)
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines.
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase.
Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38.
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase.
Cloning and expression of human mitogen-activated protein kinase kinase 7gamma1.
Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases.
Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.
The JIP group of mitogen-activated protein kinase scaffold proteins.
Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway.
The bottleneck of JNK signaling: molecular and functional characteristics of MKK4 and MKK7.