Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Architecture of the human interactome defines protein communities and disease networks.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed.
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Human GPAT/PPAT cDNA was cloned, sequenced and expressed to yield functional glutamine phosphoribosylpyrophosphate amidotransferase, the enzyme for step one of de novo purine nucleotide synthesis, whose activity requires removal of an 11-residue propeptide.
"A cDNA encoding human glutamine phosphoribosylpyrophosphate amidotransferase for"
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer
5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate