GO_REF:0000002
Gene Ontology annotation through association of InterPro records with GO terms
GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping
GO_REF:0000052
Gene Ontology annotation based on curation of immunofluorescence data
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:14623119
Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.
PMID:15094042
Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1.
PMID:15161933
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
PMID:16189514
Towards a proteome-scale map of the human protein-protein interaction network.
PMID:17368478
Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
PMID:19060904
An empirical framework for binary interactome mapping.
PMID:22678294
An oxygen-regulated switch in the protein synthesis machinery.
PMID:22681889
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
PMID:22751931
A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.
PMID:23991149
Investigating the consequences of eIF4E2 (4EHP) interaction with 4E-transporter on its cellular distribution in HeLa cells.
PMID:25416956
A proteome-scale map of the human interactome network.
PMID:25959826
Quantitative interaction proteomics of neurodegenerative disease proteins.
PMID:28487484
Cap-binding protein 4EHP effects translation silencing by microRNAs.
PMID:28514442
Architecture of the human interactome defines protein communities and disease networks.
PMID:31439631
Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
PMID:31515488
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
PMID:32726578
GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control.
PMID:32814053
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
PMID:33053355
4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay.
PMID:33961781
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
PMID:35271311
OpenCell: Endogenous tagging for the cartography of human cellular organization.
PMID:35878012
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
PMID:40205054
Multimodal cell maps as a foundation for structural and functional genomics.
PMID:9582349
Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein.
Reactome:R-HSA-1678842
Reactome pathway annotation (cytosol localization)
Reactome:R-HSA-1678843
Reactome pathway annotation (cytosol localization)
file:human/EIF4E2/EIF4E2-uniprot.txt
UniProt entry O60573 (IF4E2_HUMAN)
file:human/EIF4E2/EIF4E2-goa.tsv
GOA annotations for EIF4E2
PMID:26854219
Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus.
file:human/EIF4E2/EIF4E2-hypotheses/eif4f-complex-under-hypoxia/openscientist.md
OpenScientist assessment of EIF4E2 and the eIF4F complex under hypoxia