Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling.
Type III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptor.
A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC.
Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling.
Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors.
Expression of betaglycan, an inhibin coreceptor, in normal human ovaries and ovarian sex cord-stromal tumors and its regulation in cultured human granulosa-luteal cells.
Human colostrum: identification of minor proteins in the aqueous phase by proteomics.
Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia.
Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.
The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors.
Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma.
TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells.
miR-19a and miR-424 target TGFBR3 to promote epithelial-to-mesenchymal transition and migration of tongue squamous cell carcinoma cells.
MicroRNA let-7a regulates angiogenesis by targeting TGFBR3 mRNA.
Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts.
A physical wiring diagram for the human immune system.
Endocytosis of TGFBR3:ARRB complex
TGFBR3 phosphorylation by TGFBR2 complex
TGFBR3_mem cleavage by MMPs
TGFBR3(1-783) binds to TGFB1,TGFB2
TGFBR3(784-851) degradation
TGFBR3 binding to ARRB1/2
FGF2:TGFBR3 binding to GIPC1
Inhibin-A binding to TGFBR3
TGFBR3 translocation to plasma membrane
TGFBR3 complex binds to TGFBR2
InhibinA-TGFBR3 binding to ACVR2A
Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling.
Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.
Coronary vessel development is dependent on the type III transforming growth factor beta receptor.
The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2.
The cytoplasmic domain of TGFβR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior.
TGFβ and BMP-2 regulate epicardial cell invasion via TGFβR3 activation of the Par6/Smurf1/RhoA pathway.
BMP2 signals loss of epithelial character in epicardial cells but requires the Type III TGFβ receptor to promote invasion.
Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3).
Betaglycan (TGFBR3) Functions as an Inhibin A, but Not Inhibin B, Coreceptor in Pituitary Gonadotrope Cells in Mice.
UniProtKB entry Q03167 (TGBR3_HUMAN)