Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
The binary interacting network of the conserved oligomeric Golgi tethering complex.
Fatal outcome due to deficiency of subunit 6 of the conserved oligomeric Golgi complex leading to a new type of congenital disorders of glycosylation.
COG Complex Complexities: Detailed Characterization of a Complete Set of HEK293T Cells Lacking Individual COG Subunits.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Architecture of the human interactome defines protein communities and disease networks.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
A proteome-scale map of the SARS-CoV-2-human contactome.
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles
The COG tethering complex interacts with numerous SNAREs at the Golgi membrane
Fusion of early-endosome derived vesicles at the TGN
The COG complex and CUX1 and GOLGA5 dimers contribute to intra-Golgi vesicle tethering
Formation of cis-SNARE complex and membrane fusion in intra-Golgi retrograde traffic
The COG complex binds RABs at the Golgi membrane
The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport.
COG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integrity.
A novel syndrome of hypohidrosis and intellectual disability is linked to COG6 deficiency.
Large scale screening for novel rab effectors reveals unexpected broad Rab binding specificity.
COG6 source evidence and provenance index