Gene Ontology annotation through association of InterPro records with GO terms
Gene Ontology annotation based on Enzyme Commission mapping
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif.
70-kDa peroxisomal membrane protein related protein (P70R/ABCD4) localizes to endoplasmic reticulum not peroxisomes, and NH2-terminal hydrophobic property determines the subcellular localization of ABC subfamily D proteins.
Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism.
Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4.
Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1.
Architecture of the human interactome defines protein communities and disease networks.
Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B(12)-trafficking proteins ABCD4 and LMBD1.
The lysosomal protein ABCD4 can transport vitamin B(12) across liposomal membranes in vitro.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
Primary structure of human PMP69, a putative peroxisomal ABC-transporter.
Identification of a fourth half ABC transporter in the human peroxisomal membrane.
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells)
Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol
Uptake of dietary cobalamins into enterocytes
Transport of RCbl within the body
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol
ABCD4 UniProtKB record (O14678)