Gene Ontology annotation through association of InterPro records with GO terms
Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry A0A0H2LU38 (A0A0H2LU38_VARPD): Urease accessory protein UreE
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VPARA_50940 (A0A0H2LU38, ureE) is a 200-residue cytoplasmic urease accessory protein (HAMAP rule MF_00822, InterPro IPR012406, Pfam PF02814/PF05194) with a histidine-rich C-terminal tail that binds nickel and functions as a nickel donor during urease metallocenter assembly.
"CC -!- FUNCTION: Involved in urease metallocenter assembly. Binds nickel. CC Probably functions as a nickel donor during metallocenter assembly. CC {ECO:0000256|HAMAP-Rule:MF_00822}."
Purification and characterization of Klebsiella aerogenes UreE protein: a nickel-binding protein that functions in urease metallocenter assembly.
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Purified bacterial UreE is a cytoplasmic dimeric protein that binds nickel ions via histidyl imidazole ligands and functions as an intracellular nickel donor during urease metallocenter assembly.
"We hypothesize that UreE binds intracellular nickel ion and functions as a nickel donor during metallocenter assembly into the urease apoprotein."
Klebsiella aerogenes UreF: identification of the UreG binding site and role in enhancing the fidelity of urease activation.
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UreE functions as a metallochaperone that delivers Ni(2+) to the UreD-UreF-UreG complex bound to urease apoprotein.
"UreE functions as a metallochaperone that delivers Ni to a UreD-UreF-UreG complex bound to urease apoprotein, with UreG serving as a GTPase during enzyme activation."
Complete genome sequence of the metabolically versatile plant growth-promoting endophyte Variovorax paradoxus S110.
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Genomic analysis of Variovorax paradoxus highlights its diverse metabolic capabilities in soil and plant-associated environments.
"Variovorax paradoxus is a microorganism of special interest due to its diverse metabolic capabilities, including the biodegradation of both biogenic compounds and anthropogenic contaminants."