Gene Ontology annotation based on Enzyme Commission mapping
TreeGrafter-generated GO annotations
Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry Q88FM3 for Pseudomonas putida KT2440 liuC
Identification of genes and proteins necessary for catabolism of acyclic terpenes and leucine/isovalerate in Pseudomonas aeruginosa.
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Comparative genomics identified Liu candidates in KT2440, and growth tests supported leucine/isovalerate but not acyclic-terpene utilization by P. putida.
"while both species were able to utilize leucine and isovalerate."
The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis.
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A bacterial LiuC ortholog was structurally characterized as a methylglutaconyl-CoA hydratase-family enzyme.
"LiuC, a member of the 3-methylglutaconyl CoA hydratases (MGCH)."
OpenScientist gene research for PSEPK liuC
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The report corroborates the methylglutaconyl-CoA hydratase assignment and distal leucine-pathway context while flagging the lack of a direct KT2440 assay.
"No direct biochemical characterization of the *P. putida* LiuC protein."