ttr-52 notes

Deep research status (2026-10-05)

No provider deep-research file exists for this gene. Providers were unavailable in this environment (see the ced-1 notes). The synthesis below was made by hand from cached publications.

Function

• Secreted bridge PMID:20526330.
• Expression and localization PMID:20526330.
• Structure and interface PMID:22713871. It acts as a dimer PMID:22713871.
• PS vesicles PMID:22727702. Also NRF-5 PMID:22727700.

Background-genotype rows

• In the CED-8 paper (PMID:24225442, full text), ttr-52(tm2078) is one of the engulfment-defective backgrounds PMID:24225442.
• Unlike ced-1/6/7, ttr-52 has no published evidence for promoting the death of weakly signalled cells; it was identified in 2010, after Reddien 2001 and Hoeppner 2001. So the GO:1902742 rows are REMOVE, not MODIFY to GO:1904747. This is recorded as a suggested experiment.